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R&D Prefilled Syringe (PFS) Machine

HMPL Sterile offers the R\&D Prefilled Syringe (PFS) Machine, designed to handle 1 ml to 10 ml\* syringes with quick-change parts. It delivers 15 to 20 devices per minute at 1 ml for aqueous drugs—ideal for small-batch, high-precision pharmaceutical filling in R\&D environments.

R&D Prefilled Syringe (PFS) Machine

R&D Prefilled Syringe (PFS) Machine

The HMPL ACCUFILL RPFS R&D is an advanced, compact, and integrated system designed for the precise packaging of pre-filled syringes, pre-crimped cartridges, and vials. Engineered for R&D and exhibiting batch production, this machine is optimized for use with pre-washed and sterilized devices, ensuring maximum hygiene and efficiency throughout the filling process.A compact and combo system for comprehensive packaging of pre-filled syringes/pre-crimped cartridges and vials up to 10ml. This system is aptly suitable for the pre-washed and sterilized devices packaging process. This system has one peristaltic pump-driven filling station, one rubber stopper placement*(Interchangeable for vials with required change parts) station & one cap sealing station.All the operations are duly synchronized with the servo motor for accurate, precise performance.The system is suitable for R&D/ exhibit batch production & has a rated output @15-20 devices per minute for a 1ml fill volume.

#ModelOutput Speed
1HMPL ACCUFILL RPFS R&D15-20 Devices/ Minute L Volume @1ML Fill

Automation-B:

  • 7” Colour display
  • Panel Accessories
  • Sensor
  • AC drive
  • PLC and modular

Filling Unit:

  • Peristaltic pump-based filling unit. OR servo-based syringe (0.5 ml to 5 ml)
  • Syringe up and down through the ball screw assembly.
  • The ball screw is rotating by a servo motor.
  • Ball screw mounting plate (aluminum and SS).

Linear Vibrator and Rotary Vibrator with Bowl Unit:

  • Linear vibrator for a rubber stopper.
  • Linear vibrator for aluminium cap.
  • Rubber stopper rotary vibrator with bowl.
  • Aluminum chute for rubber stopper and aluminum cap.
  • SS 304 up-down pillar assembly for rubber stopper and aluminum cap vibrator bowl.
  • Sensor for rubber stopper in chute.

Basic Machine with Change Parts:

  • One set of star wheel and back guide (material use black or white Delrin).

Output Speed 15-20 Devices/ Minute L Volume @1ML Fill

  • Machine output 15-20 PFS per minute for a 1 ml syringe

Body Structure:

  • Square pipe structure 40*40*2.0 mm thick (material used SS 304).
  • Body doors 1.2 mm thick (material used SS304).
  • Machine top plate (material used: MS 10 mm with SS 1.5 mm cladding).
  • Door handles (material used: nylon)

Security Enclosure:

  • Cabinet structure (material SS304)
  • Cabinet doors (material used – Polycarbonate/ toughened glass).
  • Door handles & hinges (material use-SS 304 & nylon).
  • Aesthetic look at door magnet assembly (self-developed).

Indicative Operation Process: PFS/ PRE-Crimped Cartridge

  • Syringes are loaded in the swipe-in slanting conveyor manually, from where syringes are transferred to the central star wheel, where the filling process is initiated.
  • After the filling cycle completion, the syringe moves to the next station, where the stoppering process is completed.
  • A filled & stoppered syringe is released on the exit conveyor from where syringes are collated in the collection tray.

Indicative Operation Process: PFS/ PRE-Crimped Cartridge

  • Vials are loaded onto the tray manually, from where they are transferred to the central star wheel, where the filling process is initiated.
  • After the filling cycle completion, the vial moves to the next station, where the stoppering process is completed.
  • The finished vial is released on the exit conveyor from where syringes are collated in the collection tray for the cap sealing process.
Applicator Shape & MOCPre-washed & sterilized PFS/ Vials/ Pre-Crimped Glass Cartridges
Volume of Syringes1ml-10ml* Change Parts Supported
Filling MaterialWater-Based Liquid/ Suspension/ Aqueous
Output Speed15-20 devices per min @1ml for aqueous drug
DirectionLeft to Right
No. of Filling Station1 NOS
No. of Rubber Stoppering Stations1 NOS
Direction of MovementLeft to Right
Power Requirement16 AMP (Main input supply cable 1.5 sq. mm 3 core)
Power SupplySingle Phase/ 230 V AC/ 50 Hz
Accuracy± 2%
Working Height850 mm ± 50 mm Adjustable
Net Weight1100 kg Approx.
Dimension2000 mm (L) x 1000 mm (W) x 1950 mm (H) Approx.

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